Title: Bifunctional organocatalysts for the synthesis of jasminaldehyde and their derivatives
Authors: Ganga, Venkata Subba Rao; Abdi, Sayed H R; Kureshy, Rukhsana I; Khan, Noor-ul H; Bajaj, Hari C
Abstract: L-Proline in the presence of benzoic acid is found to be
an effective catalytic system for the cross-aldol condensation
of benzaldehyde with 1-heptanal under solvent free condition amongst the several amino acids screened for this
reaction. Under the optimized reaction conditions, the
desired product (e.g. jasminaldehyde) is formed up to
96% selectivity in one hour using the desired arylaldehyde:
1-alkanaldehyde ratio as low as 2:1 under controlled addition of 1-alkanaldehyde.
Description: 950-955
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